Proteins & Peptides

The NAMPT Inhibitor Screening Assay Kit is designed to measure NAMPT activity for screening and profiling applications. The key to the assay is a coupled reaction including NMNAT and ADH. NAMPT converts nicotinamide substrate to nicotinamide mononucleotide (NMN) via PRPP. NMNAT subsequently converts NMN to NAD+ , which is reduced by ADH to NADH, permitting detection of the fluorescent NADH signal.

Human CD96, also known as cluster of differentiation 96 and Tactile, GenBank Accession No. NM_198196, a.a. 22-519. This protein is fused at the C-terminus to the Fc region of Human IgG1 and an Avi-tag™, expressed in a HEK293 cell expression system and enzymatically biotin-labeled using AviTag™ technology. MW = 84 kDa. This protein runs at a higher MW by SDS-PAGE due to glycosylation.

Human CD96, also known as cluster of differentiation 96 and Tactile, GenBank Accession No. NM_198196, a.a. 22-519. This protein is fused at the C-terminus to the Fc region of Human IgG1 and an Avi-tag™, expressed in a HEK293 cell expression system and enzymatically biotin-labeled using AviTag™ technology. MW = 84 kDa. This protein runs at a higher MW by SDS-PAGE due to glycosylation.

Human FcRn also known as neonatal Fc receptor is a heterodimer of FCGRT (Fc Fragment of IgG Receptor and Transporter) and B2M (beta 2 microglobulin), GenBank Accession numbers NM_001136019 and NM_004048; a.a. 24- 297 and a.a. 1-119 respectively. FCGRT has a C-terminal His-Avi-tag. This protein is enzymatically biotinylated using AviTag™ technology. These proteins are co-expressed in a HEK293 expression system. MW = 48 kDa

Human FcRn also known as neonatal Fc receptor is a heterodimer of FCGRT (Fc Fragment of IgG Receptor and Transporter) and B2M (beta 2 microglobulin), GenBank Accession numbers NM_001136019 and NM_004048; a.a. 24- 297 and a.a. 1-119 respectively. FCGRT has a C-terminal His-Avi-tag. This protein is enzymatically biotinylated using AviTag™ technology. These proteins are co-expressed in a HEK293 expression system. MW = 48 kDa

Human FcRn, also known as Neonatal Fc receptor, GenBank Accession number NM_001136019, a.a. 212-1313 with C-terminalHis-Tag. MW = 32 kDa, expressed in an HEK293 expression system.

Human FcRn, also known as Neonatal Fc receptor, GenBank Accession number NM_001136019, a.a. 212-1313 with C-terminalHis-Tag. MW = 32 kDa, expressed in an HEK293 expression system.

Human KIR2DL3, also known as Killer cell immunoglobulin-like receptor 2DL3, KIR2DS5 and KIRCL23. GenBank Accession No. NM_015868. a.a. 22-245 fused at the C terminus to the Fc portion of human IgG1 followed by a C-termina Avi-tag™ and expressed in a HEK293 cell expression system. MW=53 kDa This protein is enzymatically biotinylated using Avi-Tag™ technology. Biotinylation is confirmed to be ≥90%. This protein runs at a higher MW due to glycosylation.

Human KIR2DL3, also known as Killer cell immunoglobulin-like receptor 2DL3, KIR2DS5 and KIRCL23. GenBank Accession No. NM_015868. a.a. 22-245 fused at the C terminus to the Fc portion of human IgG1 followed by a C-termina Avi-tag™ and expressed in a HEK293 cell expression system. MW=53 kDa This protein is enzymatically biotinylated using Avi-Tag™ technology. Biotinylation is confirmed to be ≥90%. This protein runs at a higher MW due to glycosylation.