Results for Proteins & Peptides ( 105127 )
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XL-888 is a novel and orally-bioavailable inhibitor of heat shock protein 90 (HSP90) that selectively inhibits HSP90α and HSP90β with IC50s of 22 nM and 44 nM respectively. It also exerts considerably weaker inhibition against a range of other diverse kinases with IC50 more than 3600 nM for all. In recent studies, XL-888 has exhibits strong anti-proliferative activities in a panel of tumor cells with values of IC50 ranging from 0.1 nM to 45.5 nM.
- From: €488.00
XL-888 is a novel and orally-bioavailable inhibitor of heat shock protein 90 (HSP90) that selectively inhibits HSP90α and HSP90β with IC50s of 22 nM and 44 nM respectively. It also exerts considerably weaker inhibition against a range of other diverse kinases with IC50 more than 3600 nM for all. In recent studies, XL-888 has exhibits strong anti-proliferative activities in a panel of tumor cells with values of IC50 ranging from 0.1 nM to 45.5 nM.
- From: €1,092.00
XL-888 is a novel and orally-bioavailable inhibitor of heat shock protein 90 (HSP90) that selectively inhibits HSP90α and HSP90β with IC50s of 22 nM and 44 nM respectively. It also exerts considerably weaker inhibition against a range of other diverse kinases with IC50 more than 3600 nM for all. In recent studies, XL-888 has exhibits strong anti-proliferative activities in a panel of tumor cells with values of IC50 ranging from 0.1 nM to 45.5 nM.
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Human CRTAM, also known as Cytotoxic and Regulatory T-Cell Molecule, GenBank Accession No. NM_019604, amino acids 18-286, expressed in a HEK293 expression system. This protein has a C-terminal Avi-Tag fused to the Fc region of Human IgG1 and is enzymatically biotinylated using Avi-tag™ technology. MW = 59 kDa.
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Human CRTAM, also known as Cytotoxic and Regulatory T-Cell Molecule, GenBank Accession No. NM_019604, amino acids 18-286, expressed in a HEK293 expression system. This protein has a C-terminal Avi-Tag fused to the Fc region of Human IgG1 and is enzymatically biotinylated using Avi-tag™ technology. MW = 59 kDa.
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Human Ten-eleven translocation 1 protein (TET1), methylcytosine dioxygenase TET1, Leukemiaassociated protein with a CXXC domain, CXXC-type zinc finger protein 6, GenBank Accession # NM_030625, a.a. 1418-2136(end) with N-terminal FLAG-tag, MW = 80 kDa, expressed in Sf9 cells via a baculovirus expression system.