Proteins & Peptides

Human CBL, also known as CBL-2, Cbl Proto-Oncogene, Signal Transduction Protein CBL, and Cbl Proto-Oncogene, E3 Ubiquitin Protein Ligase, Genbank Accession No. NM_005188, a.a. 49-434 with N-terminal GST-tag, expressed in an E. coli expression system. MW = 71 kDa.

Human TYK2, also known as PSCTK4, MGC126760, and MGC126762, GenBank Accession No. NM_003331, a.a. 442-1187(end), with N-terminal GST-tag, expressed in a Baculovirus-infected Sf9 cell expression system. MW = 110 kDa.

Human Ubiquitin Activating Enzyme (E1) (UBE1), also known as UBA1, GenBank Accession No. NM_003334, a.a. 2-1058(end) with N-terminal GST-tag, expressed in a Baculovirus infected Sf9 cell expression system. MW = 145 kDa.

Human secreted programmed cell death 1 (PD-1), also known as PDCD1, SLEB2, CD279 and HPD-L, GenBank Accession No. NM_005018, a.a 25-167, fused at the C-terminus to the Fc portion of human IgG1, with C-terminal Avi-tag™ expressed in a HEK293 cell expression system. MW = 44.5 kDa.

Human TET2, also known as Ten-eleven translocation 2 protein, and methylcytosine dioxygenase TET2, GenBank Accession #NM_001127208, a.a. 916-2002(end) with N-terminal FLAG-tag and C-terminal His-tag, expressed in a Baculovirus infected Sf9 cell expression system. MW = 126 kDa.

Recombinant human MDM2 (Mouse double minute 2 homolog), full length encompassing amino acids 2-498 (end). In this construct the N-terminal end of MDM2 is fused with GST. A short peptide linker placed between GST and the protein includes a PreScission Protease Cleavage Site to facilitate removal of the GST portion. The recombinant protein was affinity purified.

Human FXR also known as NR1H4, Bile Acid Receptor, and HRR1, GenBank Accession No. NM_005123, a.a. 193-472(end), with N-terminal GST-tag, expressed in a baculovirus infected Sf9 cell expression system. MW=59 kDa.

Please note this product may be subject to fees, we invite you to contact your local office. Human KRAS also known as C-K-RAS, CFC2, and K-RAS2A, GenBank Accession No. NM_033360, a.a. 2-186, with Gly12 to Cys mutation and N-terminal His-tag, expressed in an E. coli expression system. MW=23 kDa. The KRAS (G12C) mutant is constitutively active.

Human secreted Siglec8, also known as Sialic Acid Binding Ig Like Lectin 8, and SAF2, GenBank Accession No. NM_014442, a.a. 17-363, fused at the C-terminus of the Fc portion of human IgG1, with C-terminal Avi-tag™ expressed in a HEK293 cell expression system. MW = 67 kDa. This protein runs at a higher MW by SDS-PAGE due to glycosylation.