Proteins & Peptides

Recombinant human MDM2 (Mouse double minute 2 homolog), full length encompassing amino acids 2-498 (end). In this construct the N-terminal end of MDM2 is fused with GST. A short peptide linker placed between GST and the protein includes a PreScission Protease Cleavage Site to facilitate removal of the GST portion. The recombinant protein was affinity purified.

Human FXR also known as NR1H4, Bile Acid Receptor, and HRR1, GenBank Accession No. NM_005123, a.a. 193-472(end), with N-terminal GST-tag, expressed in a baculovirus infected Sf9 cell expression system. MW=59 kDa.

Please note this product may be subject to fees, we invite you to contact your local office. Human KRAS also known as C-K-RAS, CFC2, and K-RAS2A, GenBank Accession No. NM_033360, a.a. 2-186, with Gly12 to Cys mutation and N-terminal His-tag, expressed in an E. coli expression system. MW=23 kDa. The KRAS (G12C) mutant is constitutively active.

Human secreted Siglec8, also known as Sialic Acid Binding Ig Like Lectin 8, and SAF2, GenBank Accession No. NM_014442, a.a. 17-363, fused at the C-terminus of the Fc portion of human IgG1, with C-terminal Avi-tag™ expressed in a HEK293 cell expression system. MW = 67 kDa. This protein runs at a higher MW by SDS-PAGE due to glycosylation.

Human secreted Sialic Acid Binding Ig Like Lectin 15 (Siglec15)-Fc fusion protein, also known as CD33 Antigen-Like 3 (CD33L3) and HsT1361, GenBank Accession No. NM_213602, a.a. 20-263, fused at the C-terminus of the Fc portion of human IgG1, with C-terminal Avi-tag™ expressed in a HEK293 cell expression system. MW = 55 kDa.

Human recombinant Fibronectin type III domain-containing protein 5 (FNDC5), also known as Irisin, Fibronectin type III repeat-containing protein 2, and FRCP2, GenBank Accession No. NM_153756, a.a 32-143, with a C-terminal Avi-His-Tag™, expressed in a HEK293 cell expression system. MW=16 kDa. This protein runs at a higher MW by SDS-PAGE due to glycosylation.

Human recombinant Fibronectin type III domain-containing protein 5 (FNDC5), also known as Irisin, Fibronectin type III repeat-containing protein 2, and FRCP2, GenBank Accession No. NM_153756, a.a 32-143, with a C-terminal Avi-His-Tag, expressed in a HEK293 cell expression system and enzymatically biotin-labeled using Avi-tag™ technology. Biotinylation is confirmed to be ≥90%. MW=16 kDa. This protein runs at a higher MW by SDS-PAGE due to glycosylation.

Human secreted interleukin 2 receptor B (IL-2RB), also known as and IL-2 receptor B, GenBank Accession No. NM_ 000878, a.a 27-239, with a C-terminal Avi-His-Tag™, expressed in a HEK293 cell expression system. MW= 28 kDa. This protein runs at a higher MW by SDS-PAGE due to glycosylation.

CDK8/Cyclin C complex of human CDK 8, also known as K35, MGC126074, and MGC126075, GenBank Accession No. BC069634, a.a. 1-464(end) with N-terminal GST-tag, MW= 84 kDa, and human Cyclin C, also known as CCNC and CycC, GenBank Accession No. NM_005190, a.a. 1-238(end) with N-terminal GST-tag. MW= 55 kDa. Co-expressed in a Baculovirus infected Sf9 cell expression system.