Nucleic Acids

Gemcitabine is an anticancer nucleoside that interferes with DNA synthesis. Gemcitabine has been used in studies related to testicular cancer, breast cancer, ovarian cancer, non-small cell lung cancer, pancreatic cancer, and bladder cancer. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

2'-Deoxyguanosine-5'-monophosphate disodium salt is an inorganic compound that has a furanose ring. 2'-Deoxyguanosine 5'-Phosphate is a reactant involved in analysis of self-assembling in solution and nucleation / growth of G-qudruplexes, nucleophilic trapping and reductive alkylation. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Cytosine beta-D-arabinofuranoside Hydrochloride is the salt form of Cytarabine, which is a selective inhibitor of DNA synthesis and is used as an antineoplastic and antiviral. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

2'-Deoxycytidine is a deoxyribonucleotide that is used in the synthesis of DNA. 2'-Deoxycytidine has been shown to inhibit the kinase activity of IL-2 receptor and Toll-like receptor, which are proteins that regulate the immune response. 2'-Deoxycytidine also inhibits DNA polymerase activity and thermal expansion. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

5-Methyluridine is a nucleoside that is used to inhibit the replication of cells. 5-Methyluridine inhibits cellular replication by binding to ribothymidine and uridine in the nucleus, which inhibities DNA and RNA synthesis. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

5-Bromouridine is an energy-related metabolite that is a precursor of uridine. 5-Bromouridine binds to the nuclear DNA in cells, where it can act as a transcriptional regulator. 5-Bromouridine is used in the treatment of malignant brain tumors, where it can inhibit tumor growth by binding to the DNA of cancer cells and preventing the synthesis of proteins required for cell division. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

5-Iodo-2'-deoxyuridine is a nucleoside analog that inhibits the replication of viruses and other DNA-containing organisms. 2'-Deoxy-5-iodouridine also has inhibitory properties on cell nuclei, which may be due to its ability to bind with DNA and prevent the synthesis of RNA or protein. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Capecitabine is a fluoropyrimidine carbamate belonging to the class of antineoplastic agents called antimetabolites. Capecitabine is a prodrug that is selectively activated by tumor cells to its cytotoxic moiety, 5-fluorouracil (5-FU). Subsequently, 5-FU is metabolized to two active metabolites, 5-fluoro-2-deoxyuridine monophosphate (FdUMP) and 5-fluorouridine triphosphate (FUTP) by both tumor cells and normal cells. FdUMP inhibits DNA synthesis and cell division by reducing normal thymidine production, while FUTP inhibits RNA and protein synthesis by competing with uridine triphosphate for incorporation into the RNA strand. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

2'-Deoxyuridine 5'-monophosphate disodium salt is a nucleoside analog that inhibits the synthesis of DNA and RNA by inhibiting the enzyme thymidylate synthase, which prevents the formation of dTMP from deoxyuridine 5'-triphosphate. 2'-Deoxyuridine 5'-monophosphate disodium salt is also used in research as an antiviral agent against HIV, herpes simplex virus, and varicella zoster virus. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.