Nucleic Acids

Dideoxycytidine is an anti-viral and works as a reverse transcriptase inhibitor. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

2-Iodoadenosine is a chemical compound that is produced from the oxidation of uridine. It is used in the synthesis of peptides, which are important for biological processes like signal transduction and cell growth. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Nelzarabine is a drug that prevents the growth of cells by inhibiting the bcr-abl kinase, which is an intracellular target. This drug has been shown to be effective against pediatric patients with t-cell acute lymphoblastic leukemia and adults with chronic myeloid leukemia. Nelarabine has minimal toxicity in humans and is not toxic to healthy cells. It has been shown to have anti-inflammatory properties and may be used as a biomarker for autoimmune diseases. Nelarabine also inhibits angiogenesis, which may be due to its effects on nuclear DNA. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

5-Methyl-2'-deoxycytidine is a nucleoside analogue that inhibits the synthesis of DNA. 5-Methyl-2'-deoxycytidine prevents methylation of guanine, which disrupts the binding of guanine nucleotide-binding proteins to the dna template and prevents polymerase chain reactions. 2'-Deoxy-5-methylcytidine is also a methyltransferase inhibitor, which means it blocks the enzyme responsible for adding methyl groups to cytosine molecules. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

3'-O-[tert-Butyl(dimethyl)silyl]thymidine is a nucleoside analog that is chemically stable and has been shown to be a potential biomarker for the diagnosis of fetal bovine spongiform encephalopathy (BSE). 3’-O-t-Bulyldimethylsilyl thymidine binds to basic proteins in the cell nucleus and has been shown to inhibit protein synthesis in tubule cells of the kidney and skin cancer cells. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

2-Fluoroadenosine is a nucleoside that has shown high resistance to the enzyme cyclase. 2-Fluoroadenosine has been shown to inhibit the synthesis of ATP in ventricular myocardium and fat cells, as well as increase levels of adenylate kinase in blood. 2-Fluoroadenosine has also been shown to have potential as a drug target for autoimmune diseases, such as multiple sclerosis. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

(E)-5-(2-Bromovinyl)-2'-deoxyuridine is an thymidine analogue and acts as an anti-viral by inhibiting DNA plymerase. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

2',3',5'-Tri-O-acetylinosine can be used as an efficient method for bond cleavage and radiation protection. 2',3',5'-Tri-O-acetylinosine has been shown to bind to pyridinium ions, and it has been used in the synthesis of tetrapeptides with hydroxyl groups or alkylation. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

5-Me-2'-OMe Uridine is one of three oligonucleotide in platinum-derivatized homopyrimidine triplex-forming oligonucleotides (Pt-TFOs) useful in crosslinking to the transcribed strand in the human androgen receptor (AR) gene. Inhibitory activity against M. bovis and M. avium. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.