Nucleic Acids

Udp-alpha-d-n-acetylgalactosamine, disodium salt is a donor substrate for N-acetylgalactosaminyltransferases. Udp-alpha-d-n-acetylgalactosamine, disodium salt is useful in the synthesis of aryl azide derivatives that can be employed in affinity labeling of glycosyltransferases and UDP-HexNAc pyrophosphorylase. Udp-alpha-d-n-acetylgalactosamine, disodium salt can be used to treat and prevent renal inflammation association with infection. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

5'-O-Dmt-n2-isobutyryl-2'-o-methyl-d-guanosine is a nucleoside that is made using an oxime opening of the 5' position and a methylation at the 2' position. 5'-O-Dmt-n2-isobutyryl-2'-o-methyl-d-guanosine has been shown to have an affinity for tissues in a chemotactic assay. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

2'-Deoxy-2'-fluorouridine is a nucleoside analog that inhibits the replication of wild-type viruses by binding to the viral RNA. 2'-Deoxy-2'-fluorouridine has been shown to inhibit the replication of resistant mutants in vitro, and this inhibition can be reversed by increasing the concentration of 2'-deoxy-2'-fluorouridine. 2'-Deoxy-2'-fluorouridine also binds to duplexes of dsDNA with high affinity and specificity. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

(2'R)-2'-Deoxy-2'-fluoro-2'-methyluridine / PSI-6206 is the deaminated metabolite of beta-D-2'-Deoxy-2'-fluoro-2'-C-methylcytidine, an effective inhibitor of hepatitis C virus (HCV) RNA polymerase. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

5-Fluorouridine is a modified uridine nucleoside with a fluorine atom at position 5 of the uracil. 5-Fluorouridine is a highly cytotoxic metabolite of 5-fluorouracil. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

2'-Deoxy-L-guanosine is a nucleoside that shows antibiotic properties by inhibiting protein synthesis, leading to cell death. This is done by binding to the ribose phosphate backbone of DNA, phosphorylating it, and preventing the base pairing of adenosine with thymine. 2'-Deoxy-L-guanosine shows a high level of resistance against bacteria and is effective in the treatment of gram-positive bacteria. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

Adenosine is a nucleoside composed of a molecule of adenine attached to a ribose sugar molecule (ribofuranose) moiety via a beta-N9-glycosidic bond. Adenosine works in the energy transfer-as adenosine triphosphate (ATP) and adenosine diphosphate (ADP)-as well as in signal transduction as cyclic adenosine monophosphate, cAMP. It shows neuromodulatory, cytoprotective, anti-inflammatory and cardioprotective actions. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

N2-Isobutyrylguanosine is a synthetic nucleoside analog. N-Isobutyrylguanosine can be used in the syntehsis of 2'-O-(o-nitrobenzyl)-3'-thioguanosine phosphoramidite which is then used to form oligonucleotides, substrates for probing the mechanism of RNA catalysis. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.

N4-Methylcytidine is a nucleoside analogue that inhibits synthesis of human mitochondrial DNA by inhibiting bacterial enzyme uridine-cytidine kinase, which converts uridine to cytidine in the mitochondria. N4-Methylcytidine has been shown to be potent against viruses such as HIV and herpes simplex virus type 1 (HSV-1) in cell culture studies. This antiviral effect is due to the interference with viral dna replication and protein synthesis by preventing incorporation of uracil into dna and ribosomal RNA. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.