Results for Nucleic Acids ( 3143 )
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5-Ethynyl-2'-deoxyuridine (EdU) is a thymidine analog that can be incorporated into replicating DNA for detection of cell proliferations. The alkyne handler can be used for subsequent ligation to azide-containing molecules through a highly efficient click chemistry reaction. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.
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Fludarabine is a purine nucleoside derivative that disrupts ribonucleotide reductase and DNA polymerase in blood cells. Fludarabine exhibits antiproliferative activity (IC50 = 1.54 μM in RPMI cells) and triggers apoptosis through increasing Bax and decreasing Bid, XIAP, and survivin expression. Fludarabine displays anticancer activity against human hematological malignancies in vivo. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.
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Clevudine is a beta-L-nucleoside analog of thymidine with activity against hepatitis B virus (HBV). Intracellularly, clevudine is phosphorylated to its active metabolites, clevudine monophosphate and triphosphate. The triphosphate metabolite competes with thymidine for incorporation into viral DNA, thereby causing DNA chain termination and inhibiting the function of HBV DNA polymerase (reverse transcriptase). Clevudine has a long half-life and shows significant reduction of covalently closed circular DNA (cccDNA), therefore the patient is less likely to have a relapse after treatment is discontinued. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.
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Flavin Adenine Dinucleotide Disodium Salt hydrate is an adenine-containing enzymatic redox cofactor. Also known as flavin cofactors and is critical electron transporter in living systems. FAD has been used as a predominant fluorophore to study unstained eosinophils, which exhibit autofluorescence compared to other leucocytes. Reagent grade, for research purpose. Please contact us for GMP-grade inquiries.